Platelet Plug

 

  • When platelets come in contact with injured tissue they change their characteristics. They:
  start to swell
  assume irregular forms with numerous irradiating processes
  become sticky
  secrete ADP
  secrete thromboxane A
 
  • Thromboxane A and ADP react with other platelets and activate them. Thus a vicious cycle is initiated and a fairly loose plug is formed.