- An antibody matches an antigen as a key matches a lock.
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- Belong to a family of large molecules known as immunoglobulins.
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- Immunoglobulins are proteins, 150,000 - 900,000 kd.
- each has two identical heavy polypeptide chains and two identical
light chains, shaped to form a Y.
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- The tips of the Y's arms vary greatly from one antibody
to another. This creates a pocket uniquely shaped to enfold a specific
antigen. This is called the variable (V) region.
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- The stem of the Y links the antibody to other participants
in the immune defenses. This area is identical in all antibodies of
the same class, and is called the constant (C) region.
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