Enterohepatic circulation
  • Up to 94% of the bile salts are reabsorbed by active transport in the distal ilieum, enter the portal blood and pass to the liver where they are reabsorbed by the venous sinusoids.
  • around 20g of bile salts are required to digest and absorb 100g of dietary fat but only about 5 g are present at any one time and only 0.5g /day is synthesised by the liver the rest is due to recirculation.
  • on average each bile salt molecule recirculates 18 times before being lost in the faeces.