The pituitary gland could be considered as the "master
gland" of the body as, the anterior and posterior pituitary secrete
a battery of hormones that collectively influence all cells and affect
virtually all physiologic processes. On the other hand, the pituitary
galnd is highly influenced by the hypothalmus through the release
of hypothalmic hormones and factors.
Hypothalamic releasing and inhibiting hormones are
carried directly to the anterior pituitary gland via hypothalamic-hypophyseal
portal veins. Specific hypothalamic hormones bind to receptors on
specific anterior pituitary cells, modulating the release of the hormone
The release or inhibition of the pituitary hormones
is under a negative feedback mechanism.