- In the same manner as for nerve
tissue, after depolarisation, a muscle fibre
cannot be depolarises again for about 5 msec.
This is called the refractory period
and is divided into an absolute and relative
refractory periods. It should be noted that the
refractory period in a skeletal muscle lasts for
a fraction of the time of muscle twitch (average
= 5%).
- A single muscle fibre also obeys
the all or none law - a
minimal threshold stimulus would produce a
maximal response i.e. the muscle fibre would
contract fully or not at all. On the other hand
in a whole muscle, graded contractions are
possible e.g. one needs a stronger contraction to
carry a 50Kg weight than to carry a 5 gm weight.
These gradations depend on the frequency
of stimulation and on the
number of motor units stimulated.
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