Haemostasis and Blood Coagulation


  • Following injury to a blood vessel, three events follow:
  Vascular Spasm
    Immediately after a vessel is cut or ruptured, there is contraction of the vascular wall.
    This contraction results from both local nervous and myogenic reflexes.
    This spasm can last from a few minutes to even hours.
  Platelet plug
    If the rent in the vessel is small, it is usually just sealed by a platelet plug.

This involves a cascade of reactions ending in the polymerisation of fibrin that completes the sealing of the wound.