| Alternative Pathway |
|
- The alternative pathway uses factors B, D and P in
the process of activating C3 to C3b.
|
|
- It does not require the presence of antibody/antigen
reaction.
|
| Common Pathway |
|
- The common pathway has C3b cleaving C4 to C4a and C4b.
C4b cleaves C5 to C5a and C5b.
|
|
- Both C4a and C5a join C3a and are all anaphylatoxins.
|
|
- C5b will lead to the membrane attack complex C5b678
which works to insert C9 pieces into the plasma membrane of a cell to
cause osmolysis. It is also a chemotactic agent.
|
