CELLS OF THE HAEMOPOIETIC SYSTEM
Haemopoietic Stem Cells
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All blood cells are derived from the haemopoietic stem cell (HSC). |
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The HSC is a multipotent cell with extensive self-renewal and proliferative capacity that can differentiate into progenitors of all blood cell types. |
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estimated that HSC's comprise 0.01 to 0.05% of the total marrow cell population in humans. |
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stem cell transplantation, HSC and haemopoietic progenitor cells can be harvested by multiple bone marrow aspirations under general anaesthesia |
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Harvested HSCs and progenitor cells are infused through a vein into the circulation of the recipient, from where they are able to "home" to the bone marrow to reconstitute the haemopoietic system. |
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New evodence points out to the capability of these cells to produce other types of tissues such as kidney cell. |