• Stomach secretes 2-3l of gastric juice/day
  

• Principal components of Gastric Secretion

• HCL

acid denaturation of digested food

activate pepsinogens

kill ingested bacteria

• Intrinsic factor

absorption of dietary vitamin B12

important to prevent anaemia

• Pepsinogen

principle enzyme of the gastric juice

pepsinogen is the inactive form of the enzyme Pepsin

it is convert to the active form by the action of gastric juice

• Mucous

forms a gelatinous coating over the mucosal surface