Rhythmicity

  • Myogenic in origin - independent from nerve supply
  • Proof:
  Complete innervation of the heart does not stop the heart from beating e.g. Heart Transplants.
  Heart starts beating at day 21 of gestation while nerve tissue starts to be formed at day 35.

Mechanism

  The membrane of the specialised tissue is considered to be a leaky membrane - i.e. not all of the sodium and sodium/calcium channels close during the repolarisation stage.
  Inflow of sodium and calcium ions during the resting stage
  This inflow of sodium and calcium results in partial depolarisation with the result that a further increase in permeability to sodium and calium ensues
  This starts off a positive feedback mechanism that once the depolarisation reaches the threshold level, an action potential ensues.